2002/09-2007/07 Ph.D. Tsinghua University

1998/09-2002/07 Bachelor Tsinghua University

2018/07-                     School of Mathematics, Tongji University                 Professor

2017/06-2018/06         Zuse Institute Berlin, Germany                         Head of Research Group

2007/09-2018/06         Institute of Mathematics, Freie Universität Berlin, Germany         Postdoctroal fellow

2019/01                     Peking University, China.

2017/09-2017/10                University of California, Los Angeles, USA. (IPAM Long Program)

2017/05                     Rice University, USA.

2016/12                     Hong Kong University of Science and Technology, HK, China.

2016/11                     Oberwolfach Research Institute for Mathematics, Germany.

2015/06                     University of Birmingham, UK.

2015/04                     Jacobs University, Germany.

2014/03                     University of Cambridge, UK.

Representative works in recent years:

Journals:

• F. Noe, S. Olsson, J. Kohler and H. Wu, “Boltzmann generators-sampling equilibrium states of many-body systems with deep learning,”Science, (Accepted)

• H. Wu and F. Noe, “Variational approach for learning markov processes from time series data,”Journal of Nonlinear Science, 2019. (Accepted)

• H. Wu, F. Nuske, S. Klus, P. Koltai and F. Noe, “Variational Koopman models: Slow collective variables and molecular kinetics from short off-equilibrium simulations,”Journal of Chemical Physics, 2017, 146(15): 154104.

• A. Mardt, L. Pasquali,H. Wu, F. Noe, “VAMPnets for deep learning of molecular kinetics,”Nature Communications, 2018, 9(1): 5.

• S. Klus, F. Nuske, P. Koltai,H. Wu, I. Kevrekidis, C. Schutte, F. Noe, “Data-driven model reduction and transfer operator approximation,”Journal of Nonlinear Science, 2018.

• F. Litzinger, L. Boninsegna,H. Wu, F. Nüske, R. Patel, R. Baraniuk, F. Noe, C. Clementi, “Rapid Calculation of Molecular Kinetics Using Compressed Sensing,” Journal of chemical theory and computation, 14(5): 2771-2783, 2018.

• F. Paul, C. Wehmeyer, E. Abualrous,H. Wu, M. Crabtree, J. Schöneberg, J. Clarke, C. Freund, T. Weikl, and F. Noe, “Protein-peptide association kinetics beyond the seconds timescale from atomistic simulations,”Nature Communications, 2017, 8(1): 1095.

• S. Olsson,H. Wu, F. Paul, C. Clementi and F. Noe, “Combining experimental and simulation data of molecular processes via augmented Markov models,”Proceedings of the National Academy of Sciences (PNAS), 2017, 114(31): 8265-8270.

• F. Nuske,H. Wu, J.-H. Prinz, C. Clementi and F. Noe “Markov state models from short non-equilibrium simulations—Analysis and correction of estimation bias,”Journal of Chemical Physics, 2017, 146(9): 094104.

• H. Wu, F. Paul, C. Wehmeyer and F. Noe, “Multiensemble Markov models of molecular thermodynamics and kinetics,”Proceedings of the National Academy of Sciences (PNAS), 2016, 113(23): E3221-E3230.

• B. Trendelkamp-Schroer,H. Wu(co-first author), F. Paul and F. Noe, “Estimation and uncertainty of reversible Markov models,”Journal of Chemical Physics, 2015, 143(17): 174101.

• H. Wu, J. -H. Prinz and F. Noe, “Projected metastable Markov processes and their estimation with observable operator models,”Journal of Chemical Physics, 2015, 143(14): 144101.

• H. Wu, “Maximum margin clustering for state decomposition of metastable systems,”Neurocomputing2015, 164(21): 5-22.

• H. Wuand F. Noe, “Gaussian Markov transition models of molecular kinetics,”Journal of Chemical Physics, 2015, 142(8): 084104.

• H. Wu, A. Mey, E. Rosta and F. Noe, “Statistically optimal analysis of state-discretized trajectory data from multiple thermodynamic states,”Journal of Chemical Physics, 2014, 141(21): 214106.

• H. Wuand F. Noe, “Optimal estimation of free energies and stationary densities from multiple biased simulations,”Multiscale Modeling and Simulation: A SIAM Interdisciplinary Journal, 2014, 12(1): 25-54

• A. Mey,H. Wuand F. Noe, “xTRAM: Estimating equilibrium expectations from time-correlated simulation data at multiple thermodynamic states,”Physical Review X, 2014, 4(4): 041018.

• F. Noe,H. Wu, J.-H. Prinz and N. Plattner, “Projected and Hidden Markov Models for calculating kinetics and metastable states of complex molecules,”Journal of Chemical Physics, 2013, 139(18): 184114.

• H. Wu, F. Noe, “Bayesian framework for modeling diffusion processes with nonlinear drift based on nonlinear and incomplete observations,”Physical Review E, 2011, 83(3): 036705.

• J.-H. Prinz,H. Wu, M. Sarich, etc. “Markov models of molecular kinetics: Generation and Validation,”Journal of Chemical Physics, 2011, 134(17): 174105. (Times Cited: 523)

• H. Wu, F. Noe, “Probability distance based compression of hidden Markov models,”Multiscale Modeling and Simulation: A SIAM Interdisciplinary Journal, 2010, 8(5): 1838-1861.

• H. Wu, F. C. Sun and H. P. Liu, “Fuzzy particle filtering for uncertain systems,”IEEE Transactions on Fuzzy Systems, 2008, 16(5): 1114-1129.

Peer (double-blind) review conference proceedings:

• H. Wu,A. Mardt, L. Pasquali, F. Noe, “Deep generative Markov state models,” inProceedings of the conference on Neural Information Processing Systems (NIPS),Montréal, Canada, 2018. (Acceptance Rate: 21%)

• H. Wu and F. Noe, “Spectral learning of dynamic systems from nonequilibrium data,” inProceedings of the conference on Neural Information Processing Systems (NIPS), Barcelona, Spain, 2016, pp. 4179-4187. (Acceptance Rate: 22%)

• H. Wu, “A Bayesian nonparametric model for spectral estimation of metastable systems,” inProceedings of the conference on Uncertainty in artificial intelligence (UAI), Quebec City, Canada, 2014, pp. 878-887. (Acceptance Rate: 32%)